The comprehensive study about psychosocial factors and nervous basis on the impulsivity of eating disorders

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09864
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Kyoto University
• Principal Investigator: Noma Shun'ichi 京都大学, 医学研究科, 講師 (40314190)
• Co-Investigator(Kenkyū-buntansha): 上床 輝久 京都大学, 医学(系)研究科(研究院), その他 (20447973) ; 杉原 玄一 京都大学, 医学研究科, 助教 (70402261)
• Research Collaborator: YANASE Maya 京都大学, 大学院医学研究科, 助教 ; NODA Tomomi 京都大学, 大学院医学研究科, 客員研究員 ; MURAO Ema 京都大学, 大学院医学研究科, 客員研究員 ; ISOBE Masanori 京都大学, 大学院医学研究科, 客員研究員 ; KAWABATA Michiko 京都大学, 大学院医学研究科 ; MISHIMA Ryo 京都大学, 大学院医学研究科 ; TOSE Keima 京都大学, 大学院医学研究科 ; OONUMA Yoshihisa 東京大学, 大学院総合文化研究科
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 摂食障害 / 脳画像 / 感情制御 / 意思決定 / 窃盗

Outline of Final Research Achievements

On impulsivity of the patients with eating disorders, the brain image studies (Study A) and the investigation study of the prisoners because of theft (Study B) were conducted. The subjects of the Study A were the patients with eating disorders who were treated at the Kyoto University Hospital. The nervous activity levels of the patients with anorexia nervosa, binge/purging type during punishment anticipation task on the functional MRI were high. The nervous activity levels of the patients with anorexia nervosa, restricting type during reaction control task (GO-NOGO task) were activated. The scores of the Autisum Questionaire of the patients with anorexia nervosa were high. On the economic game task to estimate the ability of decision making, the rate of acceptance of unfair distribution of the patients with eating disorders was high. On the Study B, the thief behaviors occurred after the onset of the disease on 75% of the prisoners with eating disorders.

Free Research Field

精神医学