2017 Fiscal Year Final Research Report
Non-contrast breast MRI using molecular imaging of the breast with CEST-MRI
| Project/Area Number |
15K09921
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
金尾 昌太郎 京都大学, 医学研究科, 助教 (80542216)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | Breast cancer / MRI / CEST / non contrast |
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| Outline of Final Research Achievements |
Amide proton transfer(APT) Chemical Exchange Saturation Transfer（CEST）MRI is a state- of-the-art technique to detect low concentration amide molecule, and thus can indicate the concentration of mobile protein in our body. We hypothesized that APT CEST can reveal new information. Our result suggested that “hyperintensity rim on CEST MRI” is characteristic to the breast cancer. The rim may be seen in the pre treatment image and disappear. We also developed a quick version of CEST-MRI. The results will be presented in the coming academic meeting.
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| Free Research Field |
画像診断
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