2017 Fiscal Year Final Research Report
Hyperthermia at the single-cell level for purging disseminated disease with immuno-magnetic nanoparticles
| Project/Area Number |
15K09959
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MICHIHIRO Aono 愛媛大学, 理工学研究科, 教授 (00184052)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 温熱療法 / 磁性ナノ粒子 / 腹膜播種 |
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| Outline of Final Research Achievements |
Hyperthermia using magnetic nanoparticles and alternating magnetic field has been investigated in the past two decades and is promising for cancer therapy. However, in most cases, magnetic nanoparticles are simply administered by direct injection into the tumor, and the modality just treats only a few space-occupying lesions so far. We hypothesized that if the MNPs were delivered cancer specifically at the cellular level, Hyperthermia using magnetic nanoparticles would have the potential to treat various sorts of disseminated cancer diseases. The aim of this study was to seek for the cancer specific delivery system of immuno- magnetic nanoparticles and to establish the cancer selective intracellular hyperthermia.
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| Free Research Field |
消化器外科
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