2017 Fiscal Year Final Research Report
Measurement of coronary flow reserve using semiconductor SPECT.
| Project/Area Number |
15K09972
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nippon Medical School |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | SPECT / PET / 心筋血流 / 冠血流予備能 / 虚血性心疾患 |
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| Outline of Final Research Achievements |
Recently, semiconductor-SPECT equipment for myocardial examination was developed. Since high resolution and excellent sensitivity of the semiconductor detector, high quality calculation of myocardial blood flow is available with myocardial perfusion SPECT. Adenosine stress myocardial perfusion SPECT and myocardial perfusion PET were performed for patients with ischemic heart disease. Myocardial flow reserve (MFR) calculated with SPECT were significantly lower than those with PET examination. And the variation in MFR calculated with SPECT were larger than those with PET examination. For appropriate clinical application, application of global MFR is required.
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| Free Research Field |
放射線医学
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