Development of the piezo-actuator pulsed water jet system for laparoscopic liver resection

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10018
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General surgery
• Research Institution: Tohoku University
• Principal Investigator: Nakanishi Chikashi 東北大学, 大学病院, 講師 (00547408)
• Co-Investigator(Kenkyū-buntansha): 川岸 直樹 東北大学, 大学病院, 准教授 (00333807) ; 中川 敦寛 東北大学, 大学病院, 特任准教授 (10447162) ; 中野 徹 東北医科薬科大学, 医学部, 准教授 (50451571) ; 大谷 清伸 東北大学, 流体科学研究所, 特任准教授 (80536748)
• Research Collaborator: YOKOSAWA Tomoki
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: パルスジェット / 腹腔鏡下肝部分切除 / 多ノズル / 肝障害

Outline of Final Research Achievements

We assessed the feasibility of a newly developed, piezo actuator driven pulsed water jet (ADPJ) for laparoscopic liver resection in swine model. Laparoscopic liver resection was safely performed using ADPJ without increasing surgical duration or blood loss. And we built a prototype of ADPJ with three nozzles to improve resection speed. ADPJ with three nozzles improved resection speed, but it was noted experimentally that its resection speed depends on the driving voltage and pulse frequency. The physical properties of human liver were evaluated. There were significant differences in the breaking strength among three groups (cirrhotic liver parenchyma, hepatic vein, and Glisson’s sheaths). It was suggested that ADPJ can be used for liver resection in cirrhotic patients. Furthermore, animal experiments using rat model showed that ADPJ attenuate hepatic damage more than ultrasonic surgical aspirator after liver resection.

Free Research Field

肝臓外科