Diagnostic approach to breast cancer patients based on target metabolomics in saliva

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10060
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General surgery
• Research Institution: Nagoya City University
• Principal Investigator: Toyama Tatsuya 名古屋市立大学, 大学院医学研究科, 教授 (30315882)
• Co-Investigator(Kenkyū-buntansha): 豊岡 利正 静岡県立大学, 薬学部, 特任教授 (40183496) ; 吉本 信保 名古屋市立大学, 大学院医学研究科, 研究員 (10551244) ; 遠藤 友美 名古屋市立大学, 大学院医学研究科, 講師 (20566228)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 乳癌

Outline of Final Research Achievements

Eight polyamines strongly correlated with the cancer patients. A simple 1-order equation was developed for the discrimination of the breast cancer patients and healthy persons. The concordance rate of the breast cancer patients and the healthy persons by the equation was 88% and 76% on the training set, respectively, whereas those on the validation set was both 88%. The score in the equation tended to correlate with the cancer stage of the patients and increased with the more serious conditions.

Free Research Field

乳癌