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2017 Fiscal Year Final Research Report

Treatment strategy of breast cancer using micro RNA-1290

Research Project

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Project/Area Number 15K10061
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General surgery
Research InstitutionNagoya City University

Principal Investigator

Hato Yukari  名古屋市立大学, 大学院医学研究科, 研究員 (20721864)

Co-Investigator(Kenkyū-buntansha) 遠山 竜也  名古屋市立大学, 大学院医学研究科, 教授 (30315882)
吉本 信保  名古屋市立大学, 大学院医学研究科, 研究員 (10551244)
遠藤 友美  名古屋市立大学, 大学院医学研究科, 講師 (20566228)
Project Period (FY) 2015-04-01 – 2018-03-31
Keywords乳癌
Outline of Final Research Achievements

We investigated the correlations of miR-1290 and its target genes, NAT1 and FOXA1, with breast cancer prognosis. Positive correlation was observed between high NAT1 protein expression and better overall survival in breast cancer patients. Positive correlation was also observed between FOXA1 mRNA expression and disease-free survival in breast cancer patients who received neoadjuvant chemotherapy. However, no correlation was observed miR-1290 expression and prognosis in breast cancer patients.

Free Research Field

乳癌

URL: 

Published: 2019-03-29  

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