Evaluation of swallowing function by high-resolution manometry after radical resection of thoracic esophageal cancer

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10091
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Digestive surgery
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: Kamiya Kinji 浜松医科大学, 医学部附属病院, 講師 (20324361)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 食道外科学 / 食道癌 / 術後嚥下機能 / 食道内圧

Outline of Final Research Achievements

Swallowing dysfunction after radical operation of thoracic esophageal cancer would significantly influence not only a patient’s Quality of Life but also treatment outcomes. The present study aimed to clarify swallowing dynamics after esophageal cancer operation. According to the analysis of postoperative videofluorography, it was suggested that coordinated movement at each point such as tongue root, epiglottis, hyoid bone, etc. and obstacle of maximum moving distance for hyoid bone could be involved. In the evaluation with the high-resolution manometry, it can evaluate maximum swallowing pressure, minimum relaxation pressure of upper esophageal sphincter (UES) site, swallowing duration, resting pressure of residual esophagus and gastric tube, etc. In addition, swallowing disorder may possibly be caused by influence on compensatory voluntary movement, decline in swallowing pressure with UES dysfunction and increase in internal pressure of resting esophagus and gastric tube.

Free Research Field

消化器外科学