Clarification of pathophysiology and prognosis prediction of Refractory peripheral nerve neuropathy using Diffusion tensor MRI

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10421
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: Tokyo Dental College (2016-2017); Keio University (2015)
• Principal Investigator: Ochi Kensuke 東京歯科大学, 歯学部, 講師 (70445203)
• Co-Investigator(Renkei-kenkyūsha): FUJIYOSHI Kanehiro 独立行政法人国立病院機構村山医療センター, 国立病院機構村山医療センター, 医長 (80365303)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 末梢神経 / 画像診断 / 難治性末梢神経障害

Outline of Final Research Achievements

<Clinical research> We have performed diffusion tensor MRI to eight patients (six cubital tunnel syndrome patients, one spontaneous anterior interosseous nerve palsy patient, and one spontaneous posterior interosseous nerve palsy patient). We concluded that interpreting signal changes for peripheral neuropathy that does not have change in the diameter of peripheral nerve is difficult at this point of time.
<Basic research> We have evaluated our peripheral nerve injury model using clip at the Nukada Medical and Biological Research Institute. We have successfully established the injury model with high reproducibility. Although our grant period is over, we will continue our research using diffusion tensor MRI.

Free Research Field

整形外科、手の外科、末梢神経外科