Search for cancer biomarkers and clinical application, Using a probe electrospray mass spectrometry

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10581
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Urology
• Research Institution: University of Yamanashi
• Principal Investigator: YAMAGISHI Takashi 山梨大学, 大学院総合研究部, 助教 (30436860)
• Co-Investigator(Renkei-kenkyūsha): MIYAMOTO Tatsuya 山梨大学, 大学院総合研究部, 助教 (80456459) ; KAMIYAMA Manabu 山梨大学, 大学院総合研究部, 講師 (90362061) ; IHARA Tatsuya 山梨大学, 大学院総合研究部, 助教 ; TAKEDA Masayuki 山梨大学, 大学院総合研究部, 教授 (80197318)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 質量スペクトル / 膀胱癌 / 前立腺癌 / 診断装置 / 癌バイオマーカー

Outline of Final Research Achievements

The purpose of this study is to construct a screening system for prostate cancer and bladder cancer by distinguishing specific differences between the cancer patients’ and non-cancer patients’ mass spectrum obtained by probe electrospray ionization-mass spectrometry using urine. The visual differences of the mass spectrum obtained this study were not clear, and statistical analysis could not be performed because the number of samples was small. However, if it is possible to obtain thousands or more of sufficient specimens, there is a possibility that a screening system can be constructed not only by statistical analysis but also by stochastic analysis using an inductive learning machine.

Free Research Field

医歯薬学