2017 Fiscal Year Final Research Report
Mechanism of cell death for programmed necrosis against noise-induced hearing loss
| Project/Area Number |
15K10750
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 内耳 / アポトーシス / 再生 |
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| Outline of Final Research Achievements |
We first manufactured the animal models that became hearing loss induced by intense noise. In the hearing loss animal model, we elucidated the mechanism which led to the cell death (apoptosis) of inner hair cells. Finally, based on these results, we examined the method that hearing loss was treated by various kinds of approaches, and the results that might cure hearing loss in the both sides where were in hearing function / inner ear morphology were obtained.
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| Free Research Field |
医歯薬学
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