Postoperative inflammation of ocular surgery in patients with diabetetes mellitus

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10849
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Tokyo Medical University
• Principal Investigator: Yasuda Kanako 東京医科大学, 医学部, 講師 (70647461)
• Co-Investigator(Kenkyū-buntansha): 志村 雅彦 東京医科大学, 医学部, 教授 (20302135) ; 野間 英孝 東京医科大学, 医学部, 准教授 (80304442)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 糖尿病網膜症 / 術後炎症 / レーザーフレアセル / 硝子体手術

Outline of Final Research Achievements

In case of cataract and/or vitreoretinal surgery in patients with diabetes, careful observation during perioperative period should be required due to their general condition of chronic inflammation. In our study, dynamic chages of post operative inflammtion after cataract/vitreoretinal surgery were disclosed. Compared to non-diabetic patients, even before the surgery, ocular inflammation evaluated by laser flare cell score showed higher value. In addition, postoperative inflammation showed higher and longer status in eyes with daiabetic patients. Interestingly, higher (10 times more) and longer(3 times more ) postoperative inflammation in diabetic eyes were significantly correlated to both longer operation time and more

Free Research Field

網膜硝子体