Tailor-made medicine of age-related macular degeneration using fluorescence of verteporfin

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10850
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Tokyo Women's Medical University
• Principal Investigator: Iida Tomohiro 東京女子医科大学, 医学部, 教授 (50241881)
• Co-Investigator(Kenkyū-buntansha): 丸子 一朗 東京女子医科大学, 医学部, 特任講師 (10443871) ; 古泉 英貴 琉球大学, 医学(系)研究科(研究院), 教授 (20551500)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: ベルテポルフィン / 光線力学的療法 / 滲出型加齢黄斑変性 / 蛍光撮影 / 脈絡膜新生血管

Outline of Final Research Achievements

Photodynamic therapy using verteporfin is an effective treatment for eyes with exudative age-related macular degeneration. To constract the tailor-made medicine of age-related macular degeneration, we examined fluorescence of verteporfin in vivo. Using fundus camera, we found fluorescence of verteporfin in retinal vessels and experimental choroidal neovascularization in rat eyes. However, we did not find fluorescence of verteporfin using fundus camera in eye with exudative age-related macular degeneration.

Free Research Field

眼科学