High b-value diffusion-weighetd imaging of head and neck lesions

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K11078
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Nagasaki University
• Principal Investigator: SUMI Misa 長崎大学, 医歯薬学総合研究科(歯学系), 准教授 (90284702)
• Co-Investigator(Kenkyū-buntansha): 中村 卓 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (30172406) ; 佐々木 美穂 長崎大学, 病院(歯学系), 助教 (10437874) ; 高木 幸則 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (30295084) ; 榮田 智 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (80325662)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: DWI / 高b値DWI

Outline of Final Research Achievements

Diffusion-weighted MR imaging (DWI) reflects the differences in the rate of diffusion of water molecules. The contrast of the image depends on the b-value representing the magnitude of the gradient magnetic field, and if the b-value is set high, the motion of the slow water molecule is targeted for imaging. Therefore, DWI (high b-value DWI) using the high b value is expected to provide information on the microstructure of the cells that could not be obtained with conventional images.
In this study, low to high multiple b-value DWI was performed on patients with various head and neck tumors, and the various parameters obtained were compared with the pathological tissues. As a result, it was suggested the usefulness of high b-value DWI in head and neck tumor diagnosis.

Free Research Field

歯科放射線学