Three-dimensional analysis of masticatory muscle local activity with spatial normalization and statistical imaging

2018 Fiscal Year Final Research Report

• Project/Area Number: 15K11191
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Tohoku University
• Principal Investigator: Yamaguchi Satoshi 東北大学, 大学病院, 講師 (50400263)
• Research Collaborator: WATANABE makoto
• Project Period (FY): 2015-04-01 – 2019-03-31
• Keywords: 咀嚼筋 / MRI

Outline of Final Research Achievements

This study was started with the aim of three-dimensional visualizing masticatory muscle internal activity by applying spatial normalization and statistical imageing when analyzing the masticatory muscle activity with mfMRI. First, the characteristics of T2 shift associated with exercise within the masticatory muscles were clarified by comparison with electromyographic measurements. Second, a technique for spatial normalization of the masticatory muscles was established and its accuracy was verified. The results of this study suggested the possibility of visualizing the masticatory muscle local activity common to the subject group, and the basis of the method was established.

Free Research Field

医歯薬学

Academic Significance and Societal Importance of the Research Achievements

骨格筋機能的磁気共鳴画像（muscle functional magnetic resonance imaging: mfMRI）によって、咀嚼筋の内部における活動、さらにはその機能の分布を統計学的に解析する方法を確立することを目的に研究を行い、解析手法の基盤となるデータを得た。筋内部の局所的活動は個人差が大きく、被験者群やタスクに共通する特徴を統計学的に解明することは、筋機能の維持や回復の効率化に寄与すると考えられる。