2017 Fiscal Year Final Research Report
Differential analysis and application at the molecular level of the immunosuppressant action base seen from cartilage tissue
Project/Area Number |
15K11248
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Surgical dentistry
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Research Institution | Okayama University |
Principal Investigator |
NAKATA naoki 岡山大学, 医歯薬学総合研究科, 助教 (90626251)
|
Co-Investigator(Kenkyū-buntansha) |
山近 英樹 岡山大学, 大学病院, 講師 (10294422)
滝川 正春 岡山大学, 医歯薬学総合研究科, 教授 (20112063)
森谷 徳文 岡山大学, 医歯薬学総合研究科, 助教 (60467751)
久保田 聡 岡山大学, 医歯薬学総合研究科, 教授 (90221936)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Keywords | 免疫抑制剤 / ステロイド |
Outline of Final Research Achievements |
1) We tried to clarify the regulatory mechanism of CCN2 / CTGF gene expression of tacrolimus in vitro using molecular biological methods, but we could not obtain the expected results. 2) When stimulating HCS-2/8 cells with tacrolimus, analyze exhaustively as well as other variable genes such as dexamethasone, using the microarray method at the time and concentration where CCN2 / CTGF gene expression regulation is the most active Although it was scheduled to do, it could not be achieved due to delay in planning progress.
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Free Research Field |
口腔外科学
|