2017 Fiscal Year Final Research Report
NLRP3 Inflammasome in onset periodotitis
Project/Area Number |
15K11396
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Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Periodontology
|
Research Institution | Nagasaki University |
Principal Investigator |
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Keywords | 歯周炎 / T細胞 |
Outline of Final Research Achievements |
The onset and progression of periodontitis involve bacterial infection and the immune response. T cells function in the immune response and reportedly induce bone resorption in inflammatory bone loss. However, the exact role of T cells in periodontal destruction remains unclear. Using our experimental model of periodontitis, we aimed to investigate the influence of T cells on periodontal destruction.
|
Free Research Field |
歯周病
|