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2017 Fiscal Year Final Research Report

NLRP3 Inflammasome in onset periodotitis

Research Project

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Project/Area Number 15K11396
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Periodontology
Research InstitutionNagasaki University

Principal Investigator

NAKAMURA Hirotaka  長崎大学, 病院(歯学系), 講師 (70346914)

Project Period (FY) 2015-04-01 – 2018-03-31
Keywords歯周炎 / T細胞
Outline of Final Research Achievements

The onset and progression of periodontitis involve bacterial infection and the immune response. T cells function in the immune response and reportedly induce bone resorption in inflammatory bone loss. However, the exact role of T cells in periodontal destruction remains unclear. Using our experimental model of periodontitis, we aimed to investigate the influence of T cells on periodontal destruction.

Free Research Field

歯周病

URL: 

Published: 2019-03-29  

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