Effects of green tea extract intake during lactation on the obesity-related metabolism in adult rat offspring predisposed by maternal nutritional status

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K12358
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Eating habits
• Research Institution: Aomori University of Health and Welfare
• Principal Investigator: KATAOKA Saori 青森県立保健大学, 健康科学部, 助手 (30712343)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 妊娠期・授乳期過栄養 / 肥満 / 脂質代謝 / 腎障害 / 緑茶抽出物

Outline of Final Research Achievements

The fetal and neonatal environments are known to be associated with the subsequent development of diseases as adults. We investigated whether green tea extract (GTE) intake during lactation affects inflammation in adipose tissue and kidneys of the high-fat diet-fed adult offspring from dams fed a high fat diet during pregnancy and lactation. GTE intake during lactation attenuated the expanded tubulointerstitial fibrosis in the kidneys and suppressed macrophage infiltration in the kidneys and adipose tissue of high-fat diet-fed adult offspring programmed by maternal intake high fat diet.

Free Research Field

食生活学