Microcirculation analysis for development of ultra small artificial heart for children

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K12503
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: Tohoku University
• Principal Investigator: Inoue Yusuke 東北大学, 加齢医学研究所, 助教 (80611079)
• Co-Investigator(Renkei-kenkyūsha): ABE Yusuke 東京大学, 大学院医学系研究科, 准教授 (90193010) ; ISOYAMA Takashi 東京大学, 大学院医学系研究科, 講師 (20302789)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 循環生理学 / 微小循環解析 / 人工心臓 / 顕微鏡 / 医工学

Outline of Final Research Achievements

The observation device consisted of camera and scaffold. The observation device can observe microcirculation of artificial heart driven by continuous flow and pulsatile flow in real time. Observation was carried out under the condition that the average blood pressure and the average blood flow rate per minute were kept constant. Under these conditions, no significant change was observed in the microcirculation and it was found that there was no inferiority of continuous flow.

Free Research Field

循環生理医工学