Development of innovative intravascular liquid embolization using light curing method

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K12535
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: The University of Tokyo
• Principal Investigator: Oishi Masamichi 東京大学, 生産技術研究所, 技術専門職員 (70396901)
• Co-Investigator(Renkei-kenkyūsha): OSHIMA Marie 東京大学, 大学院情報学環, 教授 (40242127)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 動脈瘤 / 塞栓術 / 光硬化樹脂 / 血管内治療

Outline of Final Research Achievements

In this study, in the intravascular treatment method called "embolization" which fills an embolic material inside of the aneurysm to prevent rupture, we tried to develop "light curing embolization" using light-curing liquid resin instead of conventional metal coil. As a necessary condition for the safe and efficient embolization, hydrodynamic investigations such as pulling back the embolus material injected from the catheter and preventing outflow of the embolus material to the downstream due to blood flow, and the optical and photochemical design which control light curing of the embolic material were conducted. To realize this method, we aim to achieve versatility that can apply to various sizes and shapes of aneurysm and conduct the experiment under the imaging environment in actual surgery using image diagnostic equipment.

Free Research Field

工学