2017 Fiscal Year Final Research Report
Branch analysis of biopolymers based on voltage-controlled single molecule translocation across a solid-state nanopore
| Project/Area Number |
15K13294
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanomaterials chemistry
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| Research Institution | Tokyo Denki University (2017)
Institute of Physical and Chemical Research (2015-2016) |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | ナノポア / 多糖類 / 分岐 / FPGA |
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| Outline of Final Research Achievements |
Sequential analysis of single molecule was performed using a solid-state nanopore, a small hole fabricated on thin membrane. Driving force of the translocation across the membrane is mainly an electrophoretic force based on the voltage applied across the membrane. By changing this voltage level and/or sign just after the entrance of each molecule into the nanopore, we tried to control the speed and/or direction of the translocation of the molecule.
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| Free Research Field |
ナノバイオサイエンス
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