2016 Fiscal Year Final Research Report
| Project/Area Number |
15K13312
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanobioscience
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SUYAMA Akira 東京大学, 大学院総合文化研究科, 教授 (90163063)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | DNAデバイス / ナノテクノロジー / 自己会合 / 3Dプリンター / 積層造形法 |
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| Outline of Final Research Achievements |
DNA nanostructures are supramolecular structures made by self-assembly of DNA single-strands. They are expected to be used in fields such as material science, life science, medicine and so on. One of the causes that make it difficult to build large three-dimensional DNA nanostructures is the L-cubed problem. This problem can be solved by using the layered modeling method, which is the principle of a three-dimensional printer. In this study, we developed a nano-scale layered modeling method for constructing three-dimensional DNA nanostructures. By introducing two ports, to which the adapters with complementary DNA sequences bind specifically, into the structure of the DXAB tile forming a large two-dimensional array, we succeeded in developing DNA inks that satisfy the properties required for the nano-scale layered modeling method.
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| Free Research Field |
生物物理学
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