2017 Fiscal Year Final Research Report
| Project/Area Number |
15K13371
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Optical engineering, Photon science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 光コヒーレンストモグラフィー / 光エラストグラフィー / 偏光 |
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| Outline of Final Research Achievements |
A Jones matrix optical coherence elastography (JM-OCE) was developed. This system simultaneously visualize polarization, flow and mechanical properties of biological samples. This system possesses the lateral resolution of 20-30 um and axial resolution of around 7 um, and provides three dimensional topographies of above mentioned tissue properties.
In vitro chicken skins and porcine sclera were investigated by JM-OCE. The chicken skin measurement shows that the epidermis has low birefringence while the dermis has high birefringence. By the porcine scleral measurement, it was found that the sclera has two distinct layers including superficial layer which has layered highly birefringent structures embedded in low birefringent tissue and posterior layer which has homogeneously low-birefringent appearance. Both of the tissue showed stiff appearance in the mechanical contrast images.
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| Free Research Field |
光計測
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