Solution-Phase Structure Analaysis of Fe-Complex Catalysts based on XAFS

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K13694
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Synthetic chemistry
• Research Institution: Kyoto University
• Principal Investigator: Takaya Hikaru 京都大学, 化学研究所, 准教授 (50304035)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 鉄触媒 / クロスカップリング / 有機鉄錯体 / X線吸収分光 / XAFS / XANES / EXAFS / 反応機構

Outline of Final Research Achievements

Despite the significant progress in cross-coupling technology through the use of 3d-transition metal catalysts including iron catalysts, the large paramagnetic shifts and the related loss of spin-spin coupling information in NMR spectra often hampers solution-phase structural study of catalytic intermediates in the reaction mixture. Conventional ESR spectroscopy also suffers difficulty in measuring typical Fe+2 and Fe+3 species with S > 1/2, as they are often invisible. We therefore attempted to apply synchrotron X-ray absorption spectroscopy (XAFS) for the structural and mechanistic investigation of paramagnetic organometallic intermediates in homogeneous iron-catalyzed reactions.

Free Research Field

有機化学，有機合成化学，X線分析