Development of micro-3D tissues having capillary vessel network

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K13719
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Analytical chemistry
• Research Institution: Gunma University
• Principal Investigator: Sato Kiichi 群馬大学, 大学院理工学府, 准教授 (50321906)
• Co-Investigator(Renkei-kenkyūsha): TSUNODA Kin-ichi 群馬大学, 大学院理工学府, 教授 (30175468)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: マイクロ流体デバイス / マイクロチップ / 血管模倣デバイス / 生体模倣デバイス / 動物実験代替法

Outline of Final Research Achievements

In this research, we developed 3D tissues of muscle and fat having capillary network inside and blood vessels built in a hydrogel to realize muscle, fat, and peripheral tissue models for drug delivery and distribution studies. By using commercially available human primary cells, micro-3D tissues having capillary vessel network inside were realized. The results of this work will be applicable to various fields including drug development and risk evaluation of toxic chemicals.

Free Research Field

マイクロ分析化学