2016 Fiscal Year Final Research Report
Development of a method for imaging RNA digestion in cells and its application for studying stress response
| Project/Area Number |
15K13746
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bio-related chemistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 核酸関連化学 / RNA分解 / ストレス応答 / tRNA / FCS |
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| Outline of Final Research Achievements |
Localization change and/or degradation of RNAs have been known to associated with various cellular events. In this study, a method to observe degradation of a fluorescently labeled RNA in each place in a cell by fluorescence correlation spectroscopy. We attempted to observe heat stress-induced tRNA degradation in mammal cells by this method.
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| Free Research Field |
生体関連化学
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