Development of micro diffusion sensor using optical MEMS

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K13890
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Thermal engineering
• Research Institution: Keio University
• Principal Investigator: TAGUCHI Yoshihiro 慶應義塾大学, 理工学部(矢上), 准教授 (30433741)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 熱物性 / 熱工学 / マイクロ・ナノデバイス

Outline of Final Research Achievements

The diffusion coefficients of biological molecules, such as proteins, reflect their size, molecular structure, conformational changes, and inter-molecular interactions. Therefore, how the diffusion coefficient of biological samples changes in liquid solution is essential knowledge for clinical diagnosis and drug discovery. In this study, novel techniques such as (1) the simple fabrication technique of hydrogenated amorphous silicon, (2) the optical sorting technique for the high sensitive measurement, and (3) the new channel structure applicable for the biological sample, have been developed.

Free Research Field

ナノ・マイクロ熱工学