Searching for the "plant dynein"

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K14540
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: Nagoya University
• Principal Investigator: Goshima Gohta 名古屋大学, 理学研究科, 教授 (20447840)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 細胞内輸送 / 微小管 / ヒメツリガネゴケ / キネシン

Outline of Final Research Achievements

In animal cells, the retrograde transport of intracellular cargo along microtubules is executed by the cytoplasmic dynein motor (retrograde transport is transport towards the minus end of the microtubule). Interestingly, however, land plants have lost the cytoplasmic dynein gene, despite that they execute retrograde transport. In this research, we aim to identify the motor(s) responsible for retrograde transport in plants. Using he moss Physcomitrella patens, we identified three kinesin-14 motor proteins (KCBP, KCH, ATK) that were required for retrograde transport of the nucleus, chloroplast, and microtubule itself in the moss cytoplasm.

Free Research Field

細胞生物学