Evaluation of Brown Adipose Tissue Activity

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K14616
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Applied anthropology
• Research Institution: Kyushu University
• Principal Investigator: Maeda Takafumi 九州大学, 芸術工学研究院, 教授 (90301407)
• Co-Investigator(Kenkyū-buntansha): 米代 武司 カリフォルニア大学サンフランシスコ校, 糖尿病センター, 学振海外特別研究員 (40724167) ; 松下 真美 天使大学, 看護栄養学部, 助教 (60517316) ; 斉藤 昌之 北海道大学, 獣医学研究院, 名誉教授 (80036441)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 環境適応能 / 寒冷適応 / 機能的潜在性

Outline of Final Research Achievements

The purpose of this study was to examine the validity of supraclavicular subcutaneous tissue temperature as an index of brown adipose tissue activity. We measured the brown adipose tissue activity in winter by FDG-PET/CT method. We also performed cold exposure test and measured metabolic rate, rectal and skin temperatures, blood flow, and subcutaneous tissue temperatures at supraclavicular and breast during cold exposure for 90 min in summer and winter. As a result, the SUVmax, which was an index of brown adipose activity, was not related with supraclavicular skin temperature but related with the supraclavicular subcutaneous tissue temperature. Also the supraclavicular subcutaneous tissue temperature maintained during cold exposure in winter, but that was decreasing in summer. These results suggested that the brown adipose tissue activity was evaluated by the supraclavicular subcutaneous tissue temperature.

Free Research Field

生理人類学