Exploration of infection mechanism and utilization of a mitochondrially replicating virus

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K14663
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Plant protection science
• Research Institution: Okayama University
• Principal Investigator: SUZUKI Nobuhiro 岡山大学, 資源植物科学研究所, 教授 (70206514)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: ミトコンドリア / ミトウイルス / 菌類ウイルス

Outline of Final Research Achievements

Mitoviruses are a unique group of mitochondrially replicating viruses with positive-sense, single stranded RNA genomes. Among them is Cryphonectria mitovirus 1 (CpMV1) which infects one of the three most destructive tree pathogens, chestnut blight fungus. This pathosystem involves two host/parasite interactions (chestnut vs. chestnut blight fungus) and chestnut blight fungus vs. CpMV1). This study represents the first example in which the host range, lateral transmissibility, symptom expression and counter-defense mechanism of a mitovirus was thoroughly analyzed.

Free Research Field

ウイルス学