Search for intestinal epithelial cell-derived membrane proteins interacting with dietary fiber

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K14729
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Food science
• Research Institution: Gifu University
• Principal Investigator: YABE Tomio 岐阜大学, 応用生物科学部, 教授 (70356260)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: ペクチン / 腸管上皮細胞 / 食物繊維

Outline of Final Research Achievements

Dietary fiber is a natural health food ingredient, and has attracted a great deal of attention recently, in particular as a food material for preventing lifestyle diseases. It is clarified that the physiological function brought by dietary fiber is an action on gastrointestinal function, which is reported that dietary fiber affects interaction with intestinal contents, villus morphology, and the function of digestion and absorption in the small intestine. In this research project, we focused on the fact that dietary fiber affects physiologically active substance locally secreted in the gastrointestinal tract and is involved in cell proliferation, and we attempted to identify proteins interacting with pectin in vivo. But we could not get anything highly. We are planning to continue exploring in the future.

Free Research Field

糖質生化学