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2016 Fiscal Year Final Research Report

Studies on autoimmune responses in molecular pathology of canine demodicosis

Research Project

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Project/Area Number 15K14869
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionGifu University

Principal Investigator

MAEDA Sadatoshi  岐阜大学, 応用生物科学部, 教授 (50377694)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywords犬毛包虫症
Outline of Final Research Achievements

The skin sample obtained from a dog that had suffered canine demodicosis were successfully transplanted in three NOD-SCID mice. CD8+ lymphocytes collected from three dogs (a dog which skin had been collected, a dog with canine demodicosis, a healthy dog) were then transferred to the mice. The lymphocyte transfer did not induce any clinical signs. Forty two days after the lymphocyte transfer, a dermatopathological examination was performed and indicated no inflammation in epidermis, dermis and follicles. These were no significant difference on pathological findings among three different mice.

Free Research Field

皮膚免疫学

URL: 

Published: 2018-03-22  

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