A novel parameter to evaluate thyroid function with dual-energy CT in patients with hyperthyroidism

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K15450
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Gunma University
• Principal Investigator: Otake Hidenori 群馬大学, 大学院医学系研究科, 研究員 (60727535)
• Research Collaborator: Higuchi Tetsuya 群馬大学, 医学系研究科, 准教授 ; Tsushima Yoshito 群馬大学, 医学系研究科, 教授
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: デュアルエナジーCT / DECT / 甲状腺機能亢進症 / 甲状腺シンチグラフィー / ヨード / 甲状腺

Outline of Final Research Achievements

We employed dual-energy CT (DECT) to measure the concentration of iodine in thyroid gland. In patients with Graves' disease, the correlation between iodine concentrations (ICs) measured by DECT and CT values were evaluated and then ICs were examined for the correlation to iodine uptake ratios (IURs) by thyroid scintigraphy. Moderate correlation was seen in the comparison with ICs and CT values. However, it was lower than the result expected from phantom study. IURs at 3h had moderate correlation to ICs. In conclusion, ICs measured by DECT may predict thyroid function in patients with hyperthyroidism.

Free Research Field

放射線診断学