Focal therapeutic sclerotizing polymer for micro lung cancer

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K15517
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Respiratory surgery
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: Shimada Junichi 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (60315942)
• Research Collaborator: MASAAKI SHIMAGAKI 東レ・メディカル・新事業推進室, 主幹 ; TAKASHI TANIGUCHI TAケミカル㈱, 顧問
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 肺癌 / 樹脂 / シリコーン / 硬化療法 / エチルシアノアクリレート / 低粘度 / 重合 / エタノール放出

Outline of Final Research Achievements

In this study, we succeeded in prototype synthesis of liquid silicone resin which can be visualized under CT and MRI equipment after the reaction started with a trace amount of water and the resin cured, and, in order to improve cell membrane affinity, we focused on lipid lecithin on the cell membrane and ｄeveloped a more liquid infusible liquid curing resin. Based on the above, PCT patent application was filed in 2017 as” a solid cancer therapeutic agent".In the future, we will also develop medical devices such as puncture needles necessary for resin injection, we would like to contribute to medical treatment by developing outpatient focal therapy of micro lung cancer using the latest polymer science technology.

Free Research Field

呼吸器外科学