2016 Fiscal Year Final Research Report
Development of DNA memory device using spacers in CRISPR
| Project/Area Number |
15K15675
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | CRISPR |
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| Outline of Final Research Achievements |
In this study, we analyze fragment information (spacer sequence) contained in Clustered Regulatory Interspaced Short Palindromic Repeat (CRISPR) which is a memory region of foreign DNA existing in a non-gene region on the bacterial genome, and found a basis for development of a novel bacterial memory device. Especially when we examined the CRISPR region of group A streptococci and Streptococcus suis, although it is difficult to develop memory devices, CRISPR is highly accurate for strain typing and CRISPR also appears to be a mobile element in these bacterial species, which open new insights into this CRISPR research field.
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| Free Research Field |
環境遺伝生態学
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