2016 Fiscal Year Final Research Report
Positive reactino of Aspirin for mesenchymal stem cell therapy
| Project/Area Number |
15K15710
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 間葉系幹細胞 / アスピリン / 細胞治療 |
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| Outline of Final Research Achievements |
Mesenchymal stem cells (MSCs) have been isolated from a variety of tissues, including bone marrow, adipose and mucosa. MSCs have the capacity for self-renewal and differentiation. Reports have been published on the systemic administration of MSCs leading to functional improvements by engraftment and differentiation, thus providing a new strategy to regenerate damaged tissues. Recently, it has become clear that MSCs possess immunomodulatory properties and can therefore be used to treat diseases. However, the therapeutic effect mechanisms of MSCs are yet to be elucidated. Here, we investigated these mechanisms of improvement with Aspirin administration.
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| Free Research Field |
歯科補綴学
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