2015 Fiscal Year Final Research Report
Strategy to control bone resorption around dental implants resorting to a criterion of pathological analysis of osteocytic ciliopathy
| Project/Area Number |
15K15713
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Prosthodontics/ Dental materials science and
|
|---|
| Research Institution | Kyushu Dental College |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MASAKI CHIHIRO 九州歯科大学, 歯学部, 准教授 (60397940)
KONDO YUSUKE 九州歯科大学, 歯学部, 助教 (00611287)
MUKAIBO TARO 九州歯科大学, 歯学部, 助教 (50635117)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TAMURA AKIKO 九州歯科大学, 歯学部附属病院, 医員 (30762067)
|
|---|
| Project Period (FY) |
2015-04-01 – 2016-03-31
|
| Keywords | 歯科補綴学一般 / 歯科インプラント |
|---|
| Outline of Final Research Achievements |
In this study, we tried to clarify osteocytic cilia related signaling by shutting out mechanical stimulation and to find out biomolecules concerning inhibitive control of bone resorption. IDG-SW3 cells were cultured and, taken into differentiating condition (Day0), fluorescent development of GFP, which is expressed in cooperation with Dmp1 expression and IDG-SW3 differentiation, was confirmed. Also, primary osteocytes were acquired from long bones of Dmp1-GFP transgenic mouse, and samples are being taken under analysis.
|
| Free Research Field |
医歯薬学
|
