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2017 Fiscal Year Final Research Report

Development of ginger-containing orally disintegrating tablet with swallowing function improvement ability

Research Project

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Project/Area Number 15K16189
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits
Research InstitutionKochi University

Principal Investigator

Abe Noriaki  高知大学, 医学部附属病院, 薬剤師 (00717332)

Project Period (FY) 2015-04-01 – 2018-03-31
Keywords嚥下 / サブスタンスP / 唾液 / 口腔内崩壊錠
Outline of Final Research Achievements

In this study, we have shown the followings: (1) the amount of Substance P (SP) in saliva shows a negative correlation with age, (2) it is increased by taking ginger-containing oral disintegration (OD) tablets, (3) there is a negative correlation between functional evaluation score of swallowing by endoscopic examination and age, and (4) the swallowing score improves by taking ginger-containing OD tablets.
These results were suggested that SP in saliva may work as a clinical marker for swallowing function and ginger-containing OD tablets may improve swallowing function.

Free Research Field

臨床薬理

URL: 

Published: 2019-03-29  

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