Development of ginger-containing orally disintegrating tablet with swallowing function improvement ability

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K16189
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Eating habits
• Research Institution: Kochi University
• Principal Investigator: Abe Noriaki 高知大学, 医学部附属病院, 薬剤師 (00717332)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 嚥下 / サブスタンスP / 唾液 / 口腔内崩壊錠

Outline of Final Research Achievements

In this study, we have shown the followings: (1) the amount of Substance P (SP) in saliva shows a negative correlation with age, (2) it is increased by taking ginger-containing oral disintegration (OD) tablets, (3) there is a negative correlation between functional evaluation score of swallowing by endoscopic examination and age, and (4) the swallowing score improves by taking ginger-containing OD tablets.
These results were suggested that SP in saliva may work as a clinical marker for swallowing function and ginger-containing OD tablets may improve swallowing function.

Free Research Field

臨床薬理