2017 Fiscal Year Final Research Report
Effects of sialyl-lactose on memory in rodents
Project/Area Number |
15K16221
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Eating habits
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Research Institution | Nagoya Keizai University (2017) Chubu University (2015-2016) |
Principal Investigator |
Yamada Takashi 名古屋経済大学, 人間生活科学部管理栄養学科, 准教授 (50531860)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Keywords | シアリルラクトース |
Outline of Final Research Achievements |
In this study, we examined the effect of sialyl-lactose on memory and elucidated the mechanism in rodents. Sialyl-lactose fed 24 months-old rats and senescence accelerated prone mice were decreased serum cholesterol level and increased brain dopamine, serotonin nerve growth factor levels. In addition, memory related behaviors were improved in sialyl-lactose fed senescence accelerated prone mice. These results suggested sialyl-lactose has the maintenance effect on memory in old age.
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Free Research Field |
栄養学
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