Investigating the cross-sectional and prospective relationship between dietary acid load and cardiometabolic risk factors including glucose metabolism markers, metabolic syndrome, and type 2 diabetes

2017 Fiscal Year Annual Research Report

• Project/Area Number: 15K16227
• Research Institution: National Center for Global Health and Medicine
• Principal Investigator: アクタル シャミマ 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員 (40623731)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: Dietary acid load / PRAL / NEAP / Diet / Type 2 diabetes / Mortality

Outline of Annual Research Achievements

According to our research plan we published three papers in pair reviewed international journal. Among these, two papers are published on the topic dietary acid load score and risk of type 2 diabetes and mortality. We found that high dietary acid load score is associated with risk of type 2 diabetes among Japanese men. We also found that high dietary acid load score is associated with risk of mortality and CVD mortality particularly from heart disease. According to our research plan we completed our survey and collected data from from approximately 2,000 Japanese employees. Using these data we published a paper on the topic "Association of serum and dietary magnesium with glucose metabolism markers". I also participated in national and international conferences and exchange our findings and views with other researchers.

Research Products

• [Journal Article] Associationof dietary and serum magnesium with glucose metabolism markers: The Furukawa Nutrition and Health Study (2018)
  • Author(s): Akter S, Eguchi M, Nanri A, Kochi T, Kashino I, Kuwahara K, Hu H, Miki T, Kabe I, Mizoue T.
  • Journal Title: Clin Nutr ESPEN Volume: 24 Pages: 71-77
  • DOI: 10.1016/j.clnesp.2018.01.011
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dietary acid load and mortality among Japanese men and women: Japan Public Health Center-based prospective study (2017)
  • Author(s): Akter S, Nanri A, Mizoue T, Noda M, Sawada N, Sasazuki S, Tsugane S
  • Journal Title: American Journal of Clinical Nutrition Volume: 106(1) Pages: 146-154
  • DOI: 10.3945/ajcn.117.152876.
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] High dietary acid load is associated with increased risk of type 2 diabetes in Japanese study: The Japan Public Health Center-based Prospective Study (2017)
  • Author(s): Akter S, Kurotani K, Kashino I, Goto A, Mizoue T, Noda M, Norie Sawada N, Tsugane S
  • Journal Title: Journal of Nutrition Volume: 146(5) Pages: 1076-83
  • DOI: 10.3945/jn.115.225177
  • Peer Reviewed / Int'l Joint Research
• [Presentation] Association of dietary and serum magnesium with glucose metabolism markers: the Furukawa Nutrition and Health Study. (2018)
  • Author(s): Akter S, Nanri A, Kashino I, Kuwahara K, Hu H, Kabe I, Mizoue T.
  • Organizer: The 28th Annual Scientific Meeting of Japan Epidemiologic Association, Fukushima, Japan
• [Presentation] Serum 25-hydroxivitamin D3 and risk of type 2 diabetes among Japanese. (2017)
  • Author(s): Akter S, Kuwahara K, Matsushita Y, Nakagawa T, Konishi M, Honda T, Yamamoto S, Hayashi T, Noda M, Mizoue T.
  • Organizer: 19th Asia Pacific Diabetes Conference, Melbourne, Australia
• [Presentation] Serum fatty acid composition and incidence of type 2 diabetes in Japan (2017)
  • Author(s): Akter S, Kurotani K, Sato M, Hayashi T, Kuwahara K, Matsushita Y
  • Organizer: The 27th Annual Scientific Meeting of Japan Epidemiologic Association, Yamanashi, Japan