Exploring cortical inhibitory process following weak peripheral nerve stimuli and its clinical application : an MEG study

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K16385
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Hiroshima University
• Principal Investigator: Nakagawa Kei 広島大学, 医歯薬保健学研究科(保), 助教 (10711070)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 脳磁図 / 感覚刺激 / 抑制系 / リハビリテーション / 半球間抑制

Outline of Final Research Achievements

In the present study, we aimed to explore the neurophysiological mechanism of the cortical inhibitory process and to establish a new method for evaluation using weak peripheral nerve repetitive electrical stimuli. As a result, we were able to demonstrate a possibility to evaluate intra- and inter- cortical inhibition of the somatosensory area by using a magnetoencephalography with excellent temporal and spatial resolution. These results will be helpful in further evaluation for the central nervous system diseases. In addition, we found the possibility that voluntary movement could modulate the inter-hemispheric inhibition of the somatosensory area.

Free Research Field

リハビリテーション