Neural substrates and cognition associated with daily physical activity in older persons with cognitive decline

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K16387
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Chukyo University (2016-2017); National Center for Geriatrics and Gerontology (2015)
• Principal Investigator: HARADA Kenji 中京大学, 体育学研究科, 実験実習助手 (70736058)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 高齢者 / 身体活動 / 脳構造 / 脳活動 / resting state / VBM / DTI

Outline of Final Research Achievements

The present study aimed to elucidate relationships between daily physical activity and neural substrates in an elderly, cognitively declining population. Those with high levels of physical activity had greater functional connectivity during a resting brain state than those with lower levels of physical activity. In addition, there were no significant differences or correlations between daily physical activity and gray matter density or white matter integrity. However, elders with higher levels of physical activity had a trend of smaller left parahippocampal volumes, as compared to those with low levels of physical activity.

Free Research Field

健康・スポーツ科学