2017 Fiscal Year Final Research Report
Mechanisms underlying the anti-inflammatory activity of molecular hydrogen via chemical modification of mitochondrial biomolecules
| Project/Area Number |
15K16524
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
|
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| Research Institution | Seikei University (2017)
Nippon Medical School (2015-2016) |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 抗炎症作用 / 細胞膜 / ミトコンドリア / フリーラジカル連鎖反応 / 分子状水素 |
|---|
| Outline of Final Research Achievements |
In this study, we investigated the mechanism underlying the anti-inflammatory activity of molecular hydrogen via the regulation of biomolecules in the mitochondria. Molecular hydrogen regulated the gene expression and cell death by modifying the free radical chain reaction-dependent generation of oxidized lipid mediators.
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| Free Research Field |
分子細胞生物学
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