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2016 Fiscal Year Final Research Report

The Clarification of Molecular Mechanisms of Fatigue Underlying Fatigue Regulation Factors Using Adeno-associated Virus

Research Project

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Project/Area Number 15K16536
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

Kume Satoshi  国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, 研究員 (30708441)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywords疲労・代謝・免疫・炎症 / 予防医学 / 生物情報学 / メタボローム解析 / 電子顕微鏡技術 / モルフォミクス解析 / 網羅的微細構造解析 / 顕微鏡オントロジー
Outline of Final Research Achievements

We decided whether the fatigue regulator factors really control the fatigue behavior of the animal model with the fatigue loading, and we aimed to clarify the relationship with fatigue behavior, metabolic abnormality, and tissue inflammation. In addition, the effect of fatigue load on the microstructures of the liver tissue was comprehensively examined by the latest-type scanning electron microscope technology, and the development of tissue omics analysis " micro-morphomics " was realized.

Free Research Field

疲労科学

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Published: 2018-03-22  

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