2017 Fiscal Year Final Research Report
Researching of genes controlling the critical period of the learning in early child.
| Project/Area Number |
15K16571
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Basic / Social brain science
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 幼若期学習 / 刷込み行動 / 神経可塑性 / 臨界期 |
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| Outline of Final Research Achievements |
In this study, we used the visual imprinting behavior of chicks as a learning model and aimed at elucidating the mechanism of high neural plasticity in juvenile learning. With comprehensive gene expression analysis, we identified some peptides included a diuretic peptide family were highly expressed in the brain region, which was important for imprinting learning, at the time when imprinting can be established (critical period). And the expression level of these genes were changed after imprinting learning. Moreover, Improvement in efficiency of imprinting learning and prolongation of the critical period were observed by injection of the peptide into the brain. Analysis of the binding ability of the peptides of chicks was performed.
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| Free Research Field |
神経科学・生理学
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