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2017 Fiscal Year Final Research Report

Development of Nano-sized calcium molybdate synthesis using liposome as a template

Research Project

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Project/Area Number 15K18315
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Nuclear engineering
Research InstitutionUniversity of Tsukuba

Principal Investigator

YAMASAKI Shinya  筑波大学, 数理物質系, 助教 (70610301)

Research Collaborator KURITA Saori  
Project Period (FY) 2015-04-01 – 2018-03-31
Keywordsリポソーム / ナノ粒子 / テクネチウムジェネレーター
Outline of Final Research Achievements

The CaMoO4 nanocrystals on the liposome interface was successfully formed by adding the calcium ion. The CaMoO4 formation process was examined using liquid phase analysis and solid phase analysis. The CaMoO4 formation on the liposome was also confirmed by negative staining TEM images. The calcium ion concentration controlled the liposome aggregation. The liposome aggregation may results in the enhancement of CaMoO4 crystal growth at the interface of the liposome aggregates. The reaction time is also important for the formation of smaller CaMoO4 particles. Accordingly, it is better to shorten the reaction time to make a small particle on liposome interface (<5 minutes), and to use lower calcium concentration for prevention of liposome aggregation (<2.5 mmol dm-3). The particle size of obtained CaMoO4 was about 10 nm and this particle can be used for the neutron irradiation to make technetium efficiently.

Free Research Field

分析化学

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Published: 2019-03-29  

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