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2016 Fiscal Year Final Research Report

Sturcture-function relationship of a high-order replication initiator complex in DNA recognition and functional switching

Research Project

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Project/Area Number 15K18504
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Functional biochemistry
Research InstitutionKyushu University

Principal Investigator

Kawakami Hironori  九州大学, 薬学研究院, 助教 (50403952)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywords染色体複製 / ORC / 機能構造解析 / DNA結合 / 制御因子
Outline of Final Research Achievements

The origin recognition complex, an initiator of eukaryotic DNA replication, was extensively analyzed in vitro and in vivo. Certain structure-function relationships were identified and a novel multifaceted DNA recognition mechanism was proposed.

Free Research Field

生物学

URL: 

Published: 2018-03-22  

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