2016 Fiscal Year Final Research Report
Sturcture-function relationship of a high-order replication initiator complex in DNA recognition and functional switching
Project/Area Number |
15K18504
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Functional biochemistry
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Research Institution | Kyushu University |
Principal Investigator |
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Keywords | 染色体複製 / ORC / 機能構造解析 / DNA結合 / 制御因子 |
Outline of Final Research Achievements |
The origin recognition complex, an initiator of eukaryotic DNA replication, was extensively analyzed in vitro and in vivo. Certain structure-function relationships were identified and a novel multifaceted DNA recognition mechanism was proposed.
|
Free Research Field |
生物学
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