2016 Fiscal Year Final Research Report
Plant microRNA biogenesis through RNA 5' cap structure
Project/Area Number |
15K18822
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Applied molecular and cellular biology
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Research Institution | Osaka Prefecture University |
Principal Investigator |
Iwata Yuji 大阪府立大学, 生命環境科学研究科, 助教 (80704965)
|
Project Period (FY) |
2015-04-01 – 2017-03-31
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Keywords | マイクロRNA / シロイヌナズナ |
Outline of Final Research Achievements |
MicroRNA (miRNA) is a small non-coding RNA molecule found in eukaryotes that functions in regulation of gene expression by binding to mRNA in a sequence-dependent manner and causing mRNA degradation and/or inhibition of translation. I analyzed the molecular function of SERRATE (SE) protein, which has been shown to play important roles in Arabidopsis miRNA biogenesis. I gained insights into how SE's zinc finger domain, N-terminal domain, and C-terminal domain coordinately function to assist miRNA precursor processing by the RNaseIII family endoribonuclease Dicer-Like 1 (DCL1).
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Free Research Field |
植物分子生物学
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