2016 Fiscal Year Final Research Report
Helical chirality of helicene that creates an effective asymmetric reaction field?
| Project/Area Number |
15K18835
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Iwate Medical University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Keywords | ヘリセン / 不斉リン配位子 / Miyazaki-Newman-Kwart転位 / 硫黄官能基化ヘリセン / 光学分割 / チアヘリセン |
|---|
| Outline of Final Research Achievements |
In this study, a helicene-based phosphinite ligands has been synthesized and its catalytic activity has been evaluated using the model reaction. Furthermore, the synthesis and optical resolution of helically chiral 1-sulfur-functionalized [6]helicene have been accomplished. A novel enantiopure [7]thiahelicene has also been synthesized.
|
| Free Research Field |
有機合成化学
|
