2016 Fiscal Year Final Research Report
Studies on the polymeric alkaloids and analysis of the mechanism of cell death
| Project/Area Number |
15K18890
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Natural medicines
|
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| Research Institution | Hoshi University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | インドールアルカロイド / キョウチクトウ科 / Apocynaceae |
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| Outline of Final Research Achievements |
Four new bis-monoterpene indole alkaloids (compouds A-D) including two novel skeletons were isolated from Leuconotis griffithii. Compounds A, B, and D showed growth inhibitory activities against A549 cells by autophagy pathway.
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| Free Research Field |
天然物化学
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